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Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development, is a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating a type of serotonin receptor known as the 5-HT2C receptor in a region of the brain called the hypothalamus, which is known to control appetite.

Uses

Lorcaserin is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Lorcaserin belongs to a class of drugs known as serotonin-receptor agonists. It is thought to work by affecting a certain part of the brain that helps control your appetite.

How to use Belviq

• Read the Patient Information Leaflet if available from your pharmacist before you start taking lorcaserin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

• Take this medication by mouth with or without food as directed by your doctor, usually 2 times each day. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Lorcaserin may be habit-forming. Do not increase your dose or take this drug more often than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. If you do not lose a certain amount of weight within the first 12 weeks of treatment, you may not benefit from taking this medication and your doctor may direct you to stop taking it. Talk to your doctor for details.

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